ARAPROS® consists of 55µg of beraprost sodium, an oral prostacyclin I2 derivative.
QWhat is the function of RAPROS®?
ARAPROS® has four pharmacological effects: protective effects on vascular endothelial cells; vasodilatory effects; suppressive effects on production of inflammatory cytokines; and antiplatelet effects.
RAPROS® acts by suppressing ischemia and fibrosis through suppression of capillary decrease, suppression of interstitial inflammation and suppression of microthrombi formation.
QHow often should I administer RAPROS®?
A1 tablet of RAPROS® should be administered twice a day, after meals.
QHow long can RAPROS® be stored?
AWhen stored correctly, RAPROS® can be used up to 5 years after the date of manufacture. Please see the expiry date indicated on the outer box. Please also see the summary of product characteristics for storage conditions.
QCan RAPROS® be used to treat pregnant cats?
ASafety of RAPROS® in pregnant cats has not been established. Do not administer to pregnant cats or cats that may be pregnant.
QAre there any known precautions of RAPROS®?
ARAPROS® is contraindicated in cats with hemorrhage or bleeding tendency.
RAPROS® is for use in cats only.
A mild heart rate increase within the reference range may occur within 1 hour after administration. This effect is dose-dependent and may be avoided by reducing the dose. In rare cases, moderate anorexia may be observed.
QAre there any drugs that require particular attention when administered with RAPROS®?
AAnticoagulants, antiplatelets and thrombolytic agents:
Concomitant use of these drugs with RAPROS® may increase bleeding tendency. Pay particular attention before administering RAPROS® with these drugs in cats with hemostatic disorders.
Other prostacyclin agonists or endothelin receptor antagonists that may reduce blood pressure:
It is advisable to monitor blood pressure when administering RAPROS® with these agents.
QIs RAPROS® available outside Japan?
A
RAPROS® is currently approved and commercially available only in Japan, Hong Kong, and Taiwan. Outside these markets, it is not approved and is not commercially available through authorized distribution channels. In approved markets, RAPROS® is supplied exclusively through local authorized distributors and is not shipped directly by us to veterinary clinics or pet owners.
Please note that resale and parallel importation of RAPROS® through unauthorized channels have been identified in recent years. RAPROS® is a veterinary medicinal product intended to be prescribed by a licensed veterinarian following an appropriate clinical examination. For products obtained outside authorized distribution channels, proper storage, handling, and transportation conditions cannot be confirmed. Therefore, we are unable to guarantee the quality, efficacy, or safety of such products, and we cannot provide support for their procurement or use.
Any acquisition or use of RAPROS® outside approved markets is subject to local laws and regulations.
